WHO Pharmaceuticals Newsletter No. 1, 2016

OMS, 16 de febrero de 2016

Regulatory Matters

Amlodipine besilate............................................................................... 5

Antiretroviral medicines ...................................................................... ..5

Atovaquone ........................................................................................... 5

Azilsartan .............................................................................................. 6

Benzoyl peroxide and salicylic acid topical products ............................... 6

Bisphosphonates .................................................................................... 6

Deferasirox ............................................................................................ 7

Elvitegravir/ cobicistat/ emtricitabine/ tenofovir disoproxil fumarate and

anti-epileptic medications ........................................................................ 7

Fluoroquinolones oral antibiotics ............................................................. 7

Fomepizole ............................................................................................. 8

Fingolimod............................................................................................... 8

Interferon beta-1a ................................................................................... 8

Itraconazole ............................................................................................. 9

Lenvatinib ................................................................................................ 9

Levonorgestrel intrauterine contraceptive device (IUCD) ........................... 9

Mycophenolate mofetil ............................................................................ 10

Nintedanib ethanesulfonate ...................................................................... 10

Nivolumab .............................................................................................. 10

Ombitasvir hydrate/paritaprevir hydrate/ritonavir ...................................... 10

Peginterferon alfa-2a ............................................................................... 11

Piperacillin sodium ...................................................................................11

Posaconazole ..........................................................................................11

Repaglinide and clopidogrel .....................................................................12

Sodium glucose co-transporter 2 (SGLT2) inhibitors ................................12

Thalidomide ........................................................................................... 12

Varenicline and alcohol............................................................................ 13

Safety of Medicines

Allopurinol ..............................................................................................14

Bevacizumab ..........................................................................................14

Codeine........................................................................................... ..... 14

Finasteride ..............................................................................................15

Melatonin ............................................................................................. 15

Pazopanib ....................................................................................... ..... 15

Proton pump inhibitors ................................................................... .... 16

Rosiglitazone .................................................................................. ..... 16

Signal

Vemurafenib and Atrial fibrillation: Signal strengthening ..................... .....17

Feature

Recommendations from the 38th Annual Meeting of Representatives of

the National Pharmacovigilance Centres participating in the WHO

Programme for International Drug Monitoring .................................. ..... 24

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